Semaglutide
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Semaglutide (Sermaglutide) – GLP-1 Receptor Agonist for Metabolic Research

Semaglutide is a synthetic 31‑amino acid peptide analogue of human glucagon‑like peptide‑1 (GLP‑1) engineered for extended half‑life. It functions as a selective GLP‑1 receptor agonist, stimulating glucose‑dependent insulin secretion, delaying gastric emptying, and reducing appetite through central mechanisms. This peptide has become a standard reference tool in preclinical research for type 2 diabetes, obesity, and associated cardiometabolic conditions.

Key Research Applications:

•Type 2 Diabetes & Glycemic Control – Investigates glucose‑dependent insulin release and HbA1c reduction.

•Obesity & Energy Homeostasis – Studies appetite suppression, caloric intake, and body weight regulation.

•Cardiometabolic Research – Explores effects on lipid profiles, blood pressure, and vascular inflammation.

•Neuroendocrine & Reward Pathways – Examines GLP‑1 signalling in the central nervous system.

Product Specifications:


ParameterDetail
CAS Number910463-68-2
Molecular FormulaC₁₈₇H₂₉₁N₄₅O₅₉
Molecular Weight~4113.58 g/mol (free base)
Purity≥99% (by HPLC)
Physical FormLyophilized white powder
Storage−20°C, protect from light
Intended UseFor laboratory research use only (RUO). Not for human or veterinary use.



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